The project assumes development of a new system of surgical navigation for intraoperative precise identification of a neoplastic lesion and its radical resection. Achievement of these objectives was divided into three main parts: 1. Development of a new technology, 2. Preclinical trials in-vitro and in-vivo, 3. Clinical trials: development of an innovative method of surgical oncological treatment.
The project is mainly focused on the development and preparation for implementation of an innovative surgical navigation system using molecular mechanisms for intraoperative detection of tumor tissue by specific rAAV in order to label it in a fluoroscopic mode and thus provide conditions for complete malignancy removal with preservation of critical organ functions such as vision and hearing. The final expected result of the project is the development of innovative, customized and automated cancer surgery.